A tissue transglutaminase IgA (tTg-IgA) test is used to help doctors diagnose coeliac disease. In this autoimmune disorder, the immune system mistakenly thinks that gluten — a protein in wheat, barley, rye, and oats — is a foreign invader. It makes antibodies that attack an enzyme in the intestines called tissue transglutaminase (tTG).
This test measures IgA and IgG antibodies, essential in helping to diagnose coeliac disease and gluten sensitivity.
Due to the comprehensive scale of this profile a phlebotomy sample is needed.